Non-alcohol-related Liver and Gallbladder Disorders (priority setting in association with the JLA)

About this PSP

Launched in mid-2015, this priority setting exercise aims to identify and prioritise the questions that need to be answered by research in the area of prevention, diagnosis, support, care and treatment of non-alcohol related liver and gallbladder disorders.

The Top 10 priorities were announced in March 2019.


Articles and publications

The Top 10 Priorities

  1. What is the best treatment for people with early or very early hepatocellular carcinoma?
  2. What are the best treatments that cure or delay the progression (worsening) of primary sclerosing cholangitis (PSC)?
  3. What are the best treatments that cure or delay the progression (worsening) of non-alcohol-related fatty liver disease (NAFLD)?
  4. What is the best immunosuppressive regimen in adults undergoing liver transplantation?
  5. Should the general public be educated about NAFLD with an aim to reduce the numbers of those that have it?
  6. What are the best treatments that cure or delay the progression (worsening) of autoimmune hepatitis?
  7. What are the best treatments that cure or delay the progression (worsening) of non-alcohol-related steatohepatitis?
  8. Prior to liver transplantation, is it better to transport the donor liver using a machine which pumps blood or preservation solution through the liver (machine perfusion) or is it better to transport it in the standard way of transporting it immersed in cold preservation solution (cold storage)?
  9. What the the best treatments that cure or delay the progression (worsening) of primary biliary cholangitis?
  10. Are there any treatments that reverse the liver damage in PSC?